A Tony Lembke Site
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14th March

Mortality and HbA1c Currie www.thelancet.com Vol 375 February 6, 2010

Click here to download:
Currie - Mortality and HbA1c.pdf (217 KB)
(download)

Survival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study
Craig J Currie, John R Peters, Aodán Tynan, Marc Evans, Robert J Heine, Oswaldo L Bracco, Tony Zagar, Chris D Poole

"Interpretation Low and high mean HbA1c values were associated with increased all-cause mortality and cardiac events.
If confirmed, diabetes guidelines might need revision to include a minimum HbA1c value."

Comments from Chris Mitchell 

Looking at adjusted hazard ratios for all-cause mortality for patients on either Insulin or oral hypoglycaemics on page 485 for real world general practice patients it looks to me like are targets need revision up